1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected to bortezomib, a proteasome inhibitor Utilized in the procedure of various myeloma. Its synthesis or analyze is important for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the procedure of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-ten-one): A important compound during the synthesis of imatinib, a drug that targets distinct forms of cancer, together with Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers including breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their examine is very important for optimizing the production approach and ensuring superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilized to take care of breast most cancers, and these intermediates are associated with its creation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist used in the treatment method of breast cancer. Several intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy CAS NO.125700-67-6 drug powerful in dealing with cancers including ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the procedure of colorectal most cancers and small mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is linked to the synthesis of adamantane derivatives, that have different apps, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-4 to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of various gluconic acid derivatives, which might be Employed in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor while in the synthesis of canagliflozin, a medication made use of to deal with variety 2 diabetes by 6-dione inhibiting sodium-glucose co-transporter two (SGLT2).